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Comprar Unifex (Brand name: Probalan)

  • €0.77
  • Brand name: Probalan
  • Disponibilidad: En stock
  • Ingrediente activo: Probenecid
Unifex (Probenecid) es utilizado en el tratamiento de la gota crónica o artritis gotosa.
Otros nombres de Unifex (Brand name: Probalan): Benemid  
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500 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €1.18 €35.41
60 píldoras €0.96 €70.83 €57.30
90 píldoras €0.88 €106.24 €79.19
120 píldoras €0.84 €141.65 €101.09
180 píldoras €0.80 €212.48 €144.87
270 píldoras €0.78 €318.71 €210.54
360 píldoras €0.77 €424.95 €276.22


Unifex is used in the treatment of chronic gout or gouty arthritis. These conditions are caused by too much uric acid in the blood.


Use Unifex as directed by your doctor.

Take Unifex tablets by mouth.
Swallow the tablets with a drink of water.
Take your doses at regular intervals.

If you miss a dose of Unifex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Unifex.


Store Unifex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Unifex out of the reach of children and away from pets.


Active Ingredient: Probenecid

Unifex works by removing the extra uric acid from the body. Unifex does not cure gout, but after you have been taking it for a few months it will help prevent gout attacks. Unifex will help prevent gout attacks only as long as you continue to take it.

Unifex is also used to prevent or treat other medical problems that may occur if too much uric acid is present in the body.

Unifex is sometimes used with certain kinds of antibiotics to make them more effective in the treatment of infections.


Do not use Unifex if:

you are allergic to any ingredient in Unifex;

you have blood problems or kidney stones caused by uric acid;
the patient is a child younger than 2 years of age;

you are taking salicylates (e.g., aspirin).

Contact your doctor or health care provider right away if any of these apply to you.

Important information: 

Do not use Unifex if:


you are allergic to any ingredient in Unifex;


you have blood problems or kidney stones caused by uric acid;
the patient is a child younger than 2 years of age;


you are taking salicylates (e.g., aspirin).

Contact your doctor or health care provider right away if any of these apply to you.

Important information:

Unifex may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Unifex. Using Unifex alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks. 

Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Unifex. 
Diabetes patients - Unifex may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
Unifex may interfere with some lab tests (e.g., blood or hemoglobin urine tests, theophylline levels). Make sure your doctor and lab personnel know you are using Unifex.
Lab tests, including tests for sugar in the urine, may be required to monitor your progress. Be sure to keep all doctor and lab appointments.
Use of Unifex is not recommended in children younger than 2 years of age. Safety and effectiveness in this age group have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant while taking Unifex, discuss with your doctor the benefits and risks of using Unifex during pregnancy. Unifex is excreted in breast milk. If you are or will be breast-feeding while you are using Unifex, check with your doctor or pharmacist to discuss the risks to your baby.


Check with your doctor if any of these most common side effects persist or become bothersome:

dizziness; flushing; hair loss; headache; loss of appetite; nausea; sore gums; vomiting.

Seek medical attention right away if any of these severe side effects occur:

severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; chills; dark urine; decreased or increased urination; fever; lower back, lower stomach, genital, or inner thigh pain; persistent sore throat; severe or persistent nausea, vomiting, or stomach pain; unusual bleeding or bruising; unusual tiredness or weakness; worsening gout; yellowing of the eyes or skin.

More Information

Unifex is to be used only by the patient for whom it is prescribed. Do not share it with other people. 
If your symptoms do not improve or if they become worse, check with your doctor.

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Debemos tener en cuenta las contraindicaciones, advertencias y precauciones para no experimentar reacciones no deseadas y efectos secundarios. No obstante, algunos pacientes hipersensibles pueden experimentar reacciones adversas de diverso grado que enumeraremos en seguida. Acuda al médico sin dudarlo mucho, en el momento en que han observado los siguientes efectos secundarios y pónganse en contacto con un médico o un especialista médico en línea para eliminar el riesgo de algunas que otras graves consecuencias:


  • Fast or irregular breathing
  • puffiness or swellings of the eyelids or around the eyes
  • shortness of breath, troubled breathing, tightness in chest, or wheezing
  • changes in the skin color of the face occurring together with any of the other side effects listed here
  • or skin rash, hives, or itching occurring together with any of the other side effects listed here
  • Cloudy urine
  • cough or hoarseness
  • fast or irregular breathing
  • fever
  • pain in back and/or ribs
  • sores, ulcers, or white spots on lips or in mouth
  • sore throat and fever with or without chills
  • sudden decrease in the amount of urine
  • swelling of face, fingers, feet, and/or lower legs
  • swollen and/or painful glands
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • yellow eyes or skin
  • weight gain

More Common

  • Headache
  • joint pain, redness, or swelling
  • loss of appetite
  • nausea or vomiting (mild)

Less Common

  • Bloody urine
  • difficult or painful urination
  • lower back or side pain (especially if severe or sharp)
  • skin rash, hives, or itching (occurring without other signs of an allergic reaction)
  • Dizziness
  • flushing or redness of face (occurring without any signs of an allergic reaction)
  • frequent urge to urinate
  • sore gums
Type Small Molecule
Accession Number DB01032  (APRD00167)
Groups Approved, Investigational
  • 4-((Dipropylamino)sulfonyl)benzoic acid
  • 4-(Di-N-propylsulfamoyl)benzoesaeure
  • 4-(N,N-Dipropylsulfamoyl)benzoesaeure
  • P-(Dipropylsulfamoyl)benzoic acid
  • Probenecid acid
  • Probenecida
  • Probenecide
  • Probenecidum
UNII PO572Z7917
CAS number 57-66-9
Weight Average: 285.359
Monoisotopic: 285.103478791
Chemical Formula C13H19NO4S
4-(dipropylsulfamoyl)benzoic acid
Protein binding


Toxicity Not Available
Half life

6-12 hours

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